Table of Contents
What is the main cause of anxiety and depression?
Experiencing traumatic or stressful events, such as physical or sexual abuse, the death of a loved one, or financial problems. Going through a major life change‚ even if it was planned. Having a medical problem, such as cancer, stroke, or chronic pain. Past and/or continued traumatic events. High stress situations. Drug and/or alcohol abuse. Low self-esteem, poor self-image. As with major depression, traumatic events such as the loss of a loved one, financial problems or a high level of stress can trigger persistent depressive disorder in some people. Feelings of sadness, tearfulness, emptiness or hopelessness. Angry outbursts, irritability or frustration, even over small matters. Loss of interest or pleasure in most or all normal activities, such as sex, hobbies or sports. Sleep disturbances, including insomnia or sleeping too much. Having a health condition or serious illness can cause significant worry about issues such as your treatment and your future. Stress buildup. A big event or a buildup of smaller stressful life situations may trigger excessive anxiety — for example, a death in the family, work stress or ongoing worry about finances.
What is the relationship between anxiety and depression?
Anxiety may occur as a symptom of clinical (major) depression. It’s also common to have depression that’s triggered by an anxiety disorder, such as generalized anxiety disorder, panic disorder or separation anxiety disorder. Many people have a diagnosis of both an anxiety disorder and clinical depression. Difficult experiences in childhood, adolescence or adulthood are a common trigger for anxiety problems. Going through stress and trauma when you’re very young is likely to have a particularly big impact. Experiences which can trigger anxiety problems include things like: physical or emotional abuse. There’s no single cause of depression. It can occur for a variety of reasons and it has many different triggers. For some people, an upsetting or stressful life event, such as bereavement, divorce, illness, redundancy and job or money worries, can be the cause. Different causes can often combine to trigger depression. Depression is a serious medical condition that is associated with symptoms such as melancholy, loss of pleasure, loss of energy, difficulty in concentrating, and suicidal thoughts. Depression is both a brain disorder and a state of mind. Clinical depression is the more-severe form of depression, also known as major depression or major depressive disorder. It isn’t the same as depression caused by a loss, such as the death of a loved one, or a medical condition, such as a thyroid disorder.
What causes depression in the brain?
Research suggests that depression doesn’t spring from simply having too much or too little of certain brain chemicals. Rather, there are many possible causes of depression, including faulty mood regulation by the brain, genetic vulnerability, and stressful life events. People with clinical depression often have increased levels of monoamine oxidase A (MAO-A), an enzyme that breaks down key neurotransmitters, resulting in very low levels of serotonin, dopamine and norepinephrine. The main subcortical limbic brain regions implicated in depression are the amygdala, hippocampus, and the dorsomedial thalamus. Both structural and functional abnormalities in these areas have been found in depression. According to an fMRI study, decreased brain activity in the hippocampus was reported82 in depressive patients. Reduced gray matter volume and reduced functional activity in the hippocampus would lead to negative emotion and the inability of cognitive processing in depressive patients. According to Seligman’s learned helplessness theory, depression occurs when a person learns that their attempts to escape negative situations make no difference. As a consequence they become passive and will endure aversive stimuli or environments even when escape is possible. Studies reviewed in the meta-analysis show coffee’s anti-inflammatory properties are associated with decreased depression. Caffeine blocks mood-depressing chemicals in the brain. Caffeine blocks receptors in the brain from binding with a chemical (adenosine) that causes fatigue and depressed mood.